Gait & Posture
Volume 30, Issue 4 , Pages 452-454 , November 2009

Spatial and temporal gait parameters in Alzheimer's disease and aging

  • Neelesh K. Nadkarni

      Affiliations

    • L. C. Campbell Cognitive Neurology Research Unit, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    • Heart and Stroke Foundation-Centre for Stroke Recovery, Neuroscience Research Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    • Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    • Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
    • Corresponding Author InformationCorresponding author at: A421, L.C. Campbell Cognitive Neurology Research Unit, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, Canada M4N 3M5. Tel.: +1 416 4806100; fax: +416 480 4552.
    • ,
  • Elysha Mawji

      Affiliations

    • L. C. Campbell Cognitive Neurology Research Unit, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    • ,
  • William E. McIlroy

      Affiliations

    • Heart and Stroke Foundation-Centre for Stroke Recovery, Neuroscience Research Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    • Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    • Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
    • Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada
    • Department of Physical Therapy, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Sandra E. Black

      Affiliations

    • L. C. Campbell Cognitive Neurology Research Unit, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    • Heart and Stroke Foundation-Centre for Stroke Recovery, Neuroscience Research Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    • Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    • Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
    • Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
    • Corresponding Author InformationCorresponding author at: A421, L.C. Campbell Cognitive Neurology Research Unit, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, Canada M4N 3M5. Tel.: +1 416 4806100; fax: +416 480 4552.

Received 6 November 2008 ,Revised 24 June 2009 ,Accepted 3 July 2009.

References 

  1. Allan LM, Ballard CG, Burn DJ, Kenny RA. Prevalence and severity of gait disorders in Alzheimer's and non-Alzheimer's dementias. J Am Geriatr Soc. 2005;53(10):1681–1687
  2. Benson RR, Guttmann CR, Wei X, Warfield SK, Hall C, Schmidt JA, et al. Older people with impaired mobility have specific loci of periventricular abnormality on MRI. Neurology. 2002;58(1):48–55
  3. Camicioli R, Bouchard T, Licis L. Dual-tasks and walking fast: relationship to extra-pyramidal signs in advanced Alzheimer disease. J Neurol Sci. 2006;248(1–2):205–209
  4. Camicioli R, Licis L. Motor impairment predicts falls in specialized Alzheimer care units. Alzheimer Dis Assoc Disord. 2004;18(4):214–218
  5. Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189–198
  6. Maki BE. Gait changes in older adults: predictors of falls or indicators of fear. J Am Geriatr Soc. 1997;45(3):313–320
  7. Martinez-Martin P, Gil-Nagel A, Gracia LM, Gomez JB, Martinez-Sarries J, Bermejo F. Unified Parkinson's Disease Rating Scale characteristics and structure. The Cooperative Multicentric Group. Mov Disord. 1994;9(1):76–83
  8. Mattis S. Mental status examination for organic mental syndrome in the elderly patient. In:  Bellack R,  Karasu B editor. Geriatric psychiatry. New York: Grune & Stratton; 1976;p. 77–121
  9. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34(7):939–944
  10. Nakamura T, Meguro K, Yamazaki H, Okuzumi H, Tanaka A, Horikawa A, et al. Postural and gait disturbance correlated with decreased frontal cerebral blood flow in Alzheimer disease. Alzheimer Dis Assoc Disord. 1997;11(3):132–139
  11. Pettersson AF, Engardt M, Wahlund LO. Activity level and balance in subjects with mild Alzheimer's disease. Dement Geriatr Cognit Disord. 2002;13(4):213–216
  12. Podsiadlo D, Richardson S. The timed “Up & Go”: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991;39(2):142–148
  13. Tinetti ME, Williams TF, Mayewski R. Fall risk index for elderly patients based on number of chronic disabilities. Am J Med. 1986;80(3):429–434
  14. Verghese J, Lipton RB, Hall CB, Kuslansky G, Katz MJ, Buschke H. Abnormality of gait as a predictor of non-Alzheimer's dementia. N Engl J Med. 2002;347(22):1761–1768
  15. Wahlund LO, Barkhof F, Fazekas F, Bronge L, Augustin M, Sjogren M, et al. A new rating scale for age-related white matter changes applicable to MRI and CT. Stroke. 2001;32(6):1318–1322
  16. Webster KE, Merory JR, Wittwer JE. Gait variability in community dwelling adults with Alzheimer disease. Alzheimer Dis Assoc Disord. 2006;20(1):37–40

PII: S0966-6362(09)00197-0

doi: 10.1016/j.gaitpost.2009.07.003

Gait & Posture
Volume 30, Issue 4 , Pages 452-454 , November 2009

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