Speeding up gait initiation and gait-pattern with a startling stimulus

Abstract 

Human gait involves a repetitive leg motor pattern that emerges after gait initiation. While the automatic maintenance of the gait-pattern may be under the control of subcortical motor centres, gait initiation requires the voluntary launching of a different motor program. In this study, we sought to examine how the two motor programmes respond to an experimental manipulation of the timing of gait initiation. Subjects were instructed to start walking as soon as possible at the perception of an imperative signal (IS) that, in some interspersed trials was accompanied by a startling auditory stimulus (SAS). This method is known to shorten the latency for execution of the motor task under preparation. We reasoned that, if the two motor programmes were launched together, the gait-pattern sequence would respond to SAS in the same way as gait initiation. We recorded the gait phases and the electromyographic (EMG) activity of four muscles from the leg that initiates gait. In trials with SAS, latency of all gait initiation-related events showed a significant shortening and the bursts of EMG activity had higher amplitude and shorter duration than in trials without SAS. The events related to gait-pattern were also advanced but otherwise unchanged. The fact that all the effects of SAS were limited to gait initiation suggests that startle selectively can affect the neural structures involved in gait initiation. Additionally, the proportional advancement of the gait-pattern sequence to the end of gait initiation supports the view that gait initiation may actually trigger the inputs necessary for generating the gait-pattern sequence.

Keywords: Central pattern generator, Kinematics, Gait, Startle, Subcortical motor circuits