Gait & Posture
Volume 31, Issue 4 , Pages 483-488 , April 2010

Postural instability in Charcot-Marie-Tooth type 1A patients is strongly associated with reduced somatosensation

  • Marleen H. van der Linden

      Affiliations

    • Department of Rehabilitation, Radboud University Nijmegen Medical Centre, The Netherlands
    • ,
  • Saskia C. van der Linden

      Affiliations

    • Department of Rehabilitation, Radboud University Nijmegen Medical Centre, The Netherlands
    • ,
  • Henk T. Hendricks

      Affiliations

    • Department of Rehabilitation, Radboud University Nijmegen Medical Centre, The Netherlands
    • Neuromuscular Centre Nijmegen, Radboud University Nijmegen Medical Centre, The Netherlands
    • ,
  • Baziel G.M. van Engelen

      Affiliations

    • Department of Neurology, Radboud University Nijmegen Medical Centre, The Netherlands
    • Neuromuscular Centre Nijmegen, Radboud University Nijmegen Medical Centre, The Netherlands
    • ,
  • Alexander C.H. Geurts

      Affiliations

    • Department of Rehabilitation, Radboud University Nijmegen Medical Centre, The Netherlands
    • Neuromuscular Centre Nijmegen, Radboud University Nijmegen Medical Centre, The Netherlands
    • Corresponding Author InformationCorresponding author at: Department of Rehabilitation, 898, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. Tel.: +31 243614804; fax: +31 243619839.

Received 19 January 2009 ,Revised 23 November 2009 ,Accepted 13 February 2010.

References 

  1. Boerkoel CF, Takashima H, Garcia CA, Olney RK, Johnson J, Berry K, et al. Charcot-Marie-Tooth disease and related neuropathies: mutation distribution and genotype-phenotype correlation. Ann Neurol. 2002;51:190–201
  2. Geurts ACH, Mulder TW, Nienhuis B. Postural organization in patients with hereditary motor and sensory neuropathy. Arch Phys Med Rehabil. 1992;73:569–572
  3. Bergin PS, Bronstein AM, Murray NM, Sancovic S, Zeppenfeld DK. Body sway and vibration perception thresholds in normal aging and in patients with polyneuropathy. J Neurol Neurosurg Psychiatry. 1995;58:335–340
  4. Nashner LM. Computerized dynamic posturography. In:  Jacobson GP,  Newman CW,  Kartush JM editor. Handbook of balance function testing. San Diego: Singular Publishing Group Inc.; 1997;p. 280–307
  5. Lord SR, Clark RD, Webster IW. Postural stability and associated physiological factors in a population of aged persons. J Gerontol. 1991;46:M69–M76
  6. Simoneau GG, Ulbrecht JS, Derr JA, Becker MB, Cavanagh PR. Postural instability in patients with diabetic sensory neuropathy. Diabetes Care. 1994;17:1411–1421
  7. Niam S, Cheung W, Sullivan PE, Kent S, Gu X. Balance and physical impairments after stroke. Arch Phys Med Rehabil. 1999;80(10):1227–1233
  8. Resnick HE, Stansberry KB, Harris TB, Tirivedi M, Smith K, Morgan P, et al. Diabetes, peripheral neuropathy, and old age disability. Muscle Nerve. 2002;25(1):43–50
  9. Resnick HE, Vinik AI, Schwartz AV, Leveille SG, Brancati FL, Balfour J, et al. Independent effects of peripheral nerve dysfunction on lower-extremity physical function in old age: the Women's Health and Aging Study. Diabetes Care. 2000;23(11):1642–1647
  10. Kristinsdottir EK, Fransson PA, Magnusson M. Changes in postural control in healthy elderly subjects are related to vibration sensation, vision and vestibular asymmetry. Acta Otolaryngol. 2001;121(6):700–706
  11. Hughes MA, Duncan PW, Rose DK, Chandler JM, Studenski SA. The relationship of postural sway to sensorimotor function, functional performance, and disability in the elderly. Arch Phys Med Rehabil. 1996;77(6):567–572
  12. Simmons RW, Richardson C, Pozos R. Postural stability of diabetic patients with and without cutaneous sensory deficit in the foot. Diabetes Res Clin Pract. 1997;36(3):153–160
  13. Menz HB, Morris ME, Lord SR. Foot and ankle characteristics associated with impaired balance and functional ability in older people. J Gerontol A Biol Sci Med Sci. 2005;60(12):1546–1552
  14. Nardone A, Tarantola J, Miscio G. Loss of large-diameter spindle afferent fibres is not detrimental to the control of body sway during upright stance: evidence from neuropathy. Exp Brain Res. 2000;135:155–162
  15. Nardone A, Grasso M, Schieppati M. Balance control in peripheral neuropathy: Are patients equally unstable under static and dynamic conditions?. Gait Posture. 2006;23:364–373
  16. Fowler WM, Abresch RT, Aitkens S, Carter GT, Johnson ER, Kilmer DD, et al. Profiles of neuromuscular diseases: design of the protocol. Am J Phys Med Rehabil. 1995;74:S62–69
  17. Geurts ACH, Nienhuis B, Mulder T. Intrasubject variability of selected force-platform parameters in the quantification of postural control. Arch Phys Med Rehabil. 1993;74:1144–1150
  18. Curtin F, Schulz P. Multiple correlations and bonferroni's correction. Biol Psychiatry. 1998;44:775–777
  19. Martina IS, van Koningsveld R, Schmitz PI, van der Meche FG, van Doorn PA. Measuring vibration threshold with a graduated tuning fork in normal aging and in patients with polyneuropathy, European Inflammatory Neuropathy Cause and Treatment (INCAT) group 1. J Neurol Neurosurg Psychiatry. 1998;65(5):743–747
  20. Feng Y, Schlösser FJ, Sumpio BE. The Semmes Weinstein monofilament examination as a screening tool for diabetic peripheral neuropathy. J Vasc Surg. 2009;50(3):675–682
  21. Thoumie P, Do MC. Changes in motor activity and biomechanics during balance recovery following cutaneous and muscular deafferentation. Exp Brain Res. 1996;110(2):289–297
  22. Collins JJ, De Luca CJ, Burrows A, Lipsitz L. Age-related changes in open-loop and closed-loop postural control mechanisms. Exp Brain Res. 1995;104(3):480–492
  23. Priplata AA, Niemi JB, Harry JD, Lipsitz LA, Collins JJ. Vibrating insoles and balance control in elderly people. Lancet. 2003;362:1123–1124

PII: S0966-6362(10)00058-5

doi: 10.1016/j.gaitpost.2010.02.005

Gait & Posture
Volume 31, Issue 4 , Pages 483-488 , April 2010

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